III B.Sc., SEMESTER VI MAJOR CORE 12 - CLINICAL BIOCHEMISTRY

III B.Sc., SEMESTER VI MAJOR CORE 12 - CLINICAL BIOCHEMISTRY Unit I

DISORDERS OF CARBOHYDRATE METABOLISM

Regulation of Blood Glucose

Regulation of Blood Glucose

Regulation of Blood Glucose

Abnormal sugar levels

Abnormal sugar levels

Abnormal sugar levels

Hypo and Hyperglycemia

Glycosuria

Glycosuria

Diabetes mellitus-classification

Diabetes mellitus- metabolic changes & complications

Glucose Tolerance Test

Inborn errors of carbohydrate metabolism

Pentosuria

Fructosuria

Galactosemia

Glycogen storage disease

Unit II

DISORDERS OF AMINO ACIDS AND PROTEIN METABOLSIM

DISORDERS OF AMINO ACIDS AND PROTEIN METABOLSIM

Plasma proteins in health and diseases

Characteristics of individual plasma proteins

Dysproteinemias

Paraproteinemias

Serum Urea

Creatinine level-interpretation

Porphyria

Proteins in normal urine and renal diseases

Proteins in normal urine and renal diseases

Proteinuria

Inborn errors of amino acid metabolism

Phenylketonuria

Alkaptonuria

Tyrosinosis

Albinism

Maple – syrup syndrome

Maple – Hartnup  syndrome

Unit III

DISORDERS OF LIPID METABOLISM

Intestinal lipid disorders

Lipid transport disorders

Atherosclerosis

fatty liver

obesity

Tay sach’s disease

Niemann Pick disease

Gaucher’s disease.

Unit IV

DISORDERDS OF NUCLEIC ACID METABOLISM

Disorders of Purine and pyrimidine metabolism

Gout

High serum levels of urate, orotic aciduria,

Xanthinuri

ADA deficiency

Lesch Nyhan syndrome.

Unit V

CLINICAL ENDOCRINOLOGY

Thyroid

Thyroid

Parathyroid

pituitary and adrenal medulla

pituitary and adrenal medulla

DIAGNOSTIC ENZYMOLOGY

Use of enzymes as marker for clinical diagnosis

Alkaline phosphatase

Acid phosphatase

AST & ALT

AST (SGOT)

ALT, [SGPT]

LDH

CK and amylase

Acetyl choline esterase.